I agree with you, maiafay. Maybe that's because I write slash or yaoi, whichever you want to call it. As long as the characters are acting IC, the pairing can be made believable.
Personally, I've never tried to read or write fics from the Bible. Who would want to??? But, that's up to who does want to do it. I stick to Final Fantasy and Resident Evil, but I may try some other fandoms later.
As far as the characters in the fandoms I write, no one is sacred! Except anything involving children. I could never write something like that, or read it for that matter.